Title of article
Synthesis and in vitro activity of new methylenepiperidinyl and methylenepyrrolidinyl oxazolidinone antibacterial agents
Author/Authors
Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Jae Seok Lee، نويسنده , , Joo Hwan Cha، نويسنده , , Ae Nim Pae، نويسنده , , Yong Seo Cho، نويسنده , , Moon Ho Chang، نويسنده , , Hun Yeong Koh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2227
To page
2230
Abstract
We have prepared and evaluated the antibacterial activities of a series of substituted methylenepiperidinyl and methylenepyrrolidinyl oxazolidinones against several gram-positive strains including the resistant strains of Staphyloccus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed comparable or superior in vitro activities (MIC) to vancomycin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793331
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