Title of article
A specific anti-Helicobacter pylori agent NE2001: synthesis and its effect on the growth of H. pylori
Author/Authors
Ni Cheng، نويسنده , , Jian-Shu Xie، نويسنده , , Min-Yue Zhang، نويسنده , , Chang Shu، نويسنده , , De-Xu Zhu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
2703
To page
2707
Abstract
The synthesis and anti-Helicobacter pylori activity of a novel agent NE2001, 4-(4-methylbenzyl)-4′-[guanidinomethylbenzoyloxy] biphenyl-4-carboxylate hydrochloride, are described. NE2001 had a specific inhibitory effect on the growth of H. pylori preceded by the suppression DNA synthesis in the cell. The effects of NE2001 on RNA and protein syntheses in H. pylori were also examined.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793431
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