Title of article
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors
Author/Authors
Zhonghua Pei، نويسنده , , Xiaofeng Li، نويسنده , , Gang Liu، نويسنده , , Cele Abad-Zapatero، نويسنده , , Tom Lubben، نويسنده , , Tianyuan Zhang، نويسنده , , Stephen J. Ballaron، نويسنده , , Charles W. Hutchins، نويسنده , , James M. Trevillyan، نويسنده , , Michael R. Jirousek، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
3129
To page
3132
Abstract
A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous member, TCPTP.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793522
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