Title of article
Synthesis and in vitro analysis of atrial natriuretic peptide–albumin conjugates
Author/Authors
Roger Léger، نويسنده , , Martin Robitaille، نويسنده , , Omar Quraishi، نويسنده , , Elizabeth Denholm، نويسنده , , Corinne Benquet، نويسنده , , Julie Carette، نويسنده , , Pieter van Wyk، نويسنده , , Isabelle Pellerin، نويسنده , , Nathalie Bousquet-Gagnon، نويسنده , , Jean-Paul Castaigne، نويسنده , , Dominique Bridon، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
3571
To page
3575
Abstract
Atrial natriuretic peptide (ANP) is a clinically useful anti-hypertensive hormone. Maleimide derivatives of ANP have been synthesized and conjugated to cysteine-34 of human serum albumin. The conjugates were analyzed to assess their stability, receptor binding affinity and ability to stimulate guanylyl-cyclase activity in rat lung fibroblasts.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793613
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