Title of article
Discovery of novel PTP1b inhibitors
Author/Authors
Denise A. Ockey، نويسنده , , Thomas R. Gadek، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
389
To page
391
Abstract
A small library of 19 compounds was designed based on unique structural features of PTP1b. Utilizing electrospray ionization mass spectrometry (ESI-MS) to provide binding information about complexes of enzyme and small molecule ligands, two classes of lead compounds were discovered.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793992
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