Title of article
Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage
Author/Authors
Christos A. Kontogiorgis، نويسنده , , Dimitra J. Hadjipavlou-Litina، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
611
To page
614
Abstract
The synthesis of several novel coumarin derivatives with a 7-azomethine linkage was carried out starting from 7-formyl-coumarin. The compounds were tested in vivo for their anti-inflammatory activity and in vitro for their antioxidant ability. Compounds 3a and 3e possess significant protection against carrageenin induced rat paw edema.
Keywords
Trypsin , Chymotrypsin. , Coumarin , anti-inflammatory , antioxidant , LOX inhibitors
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794039
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