Title of article
Vancomycin disulfide derivatives as antibacterial agents
Author/Authors
YongQi Mu، نويسنده , , Matthew Nodwell، نويسنده , , John L. Pace، نويسنده , , Jeng-Pyng Shaw، نويسنده , , J. Kevin Judice، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
735
To page
738
Abstract
A series of lipidated vancomycin analogues 1 bearing disulfide bonds within their lipid chains was designed and synthesized to optimize their ADME profiles while retaining antibacterial potency. These compounds exhibited good activity against resistant organisms and low accumulation in tissues such as kidney and liver.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794064
Link To Document