Title of article
Kringle 5 peptide–albumin conjugates with anti-migratory activity
Author/Authors
Roger Léger، نويسنده , , Corinne Benquet، نويسنده , , Xicai Huang، نويسنده , , Omar Quraishi، نويسنده , , Pieter van Wyk، نويسنده , , Dominique Bridon، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
841
To page
845
Abstract
Three peptide fragments of the kringle 5 region of plasminogen and their respective N- and C-terminus maleimido derivatives conjugated to Cys34 of human serum albumin were evaluated in vitro using a human umbilical vein endothelial cell (HUVEC) migration assay and a human plasma stability assay. The N-terminus maleimido derivative of the 64 to 74 segment of kringle 5 conjugated to human serum albumin possessed remarkable anti-migratory activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794086
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