Title of article
Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR
Author/Authors
Zhicai Wu، نويسنده , , Mark E. Fraley، نويسنده , , Mark T. Bilodeau، نويسنده , , Mildred L. Kaufman، نويسنده , , Edward S. Tasber، نويسنده , , Adrienne E. Balitza، نويسنده , , George D. Hartman، نويسنده , , Kathleen E. Coll، نويسنده , , Keith Rickert، نويسنده , , Jennifer Shipman، نويسنده , , Bin Shi، نويسنده , , Laura Sepp-Lorenzino، نويسنده , , Kenneth A. Thomas، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
909
To page
912
Abstract
3,7-Diarylsubstituted imidazopyridines were designed and developed as a new class of KDR kinase inhibitors. A variety of imidazopyridines were synthesized and potent inhibitors of KDR kinase activity were identified with good aqueous solubility.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794100
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