Title of article
Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones
Author/Authors
Heesoon Lee، نويسنده , , Sungmoon Cho، نويسنده , , Kwon Namgoong، نويسنده , , Jae-Kyung Jung، نويسنده , , Jungsook Cho، نويسنده , , Sung-Il Yang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
1235
To page
1237
Abstract
A series of benzo[g]quinoxaline-5,10-dione derivatives carrying a 7-dialkylaminomethyl substituent was synthesized and their in vitro cytotoxic activities were evaluated against four human cancer cell lines (HCT-15, SK-OV-3, MD-MB-468 and T-47D). The most active compound 9d showed cytotoxic activity comparable to that of doxorubicin against HCT-15 cancer cell line.
Keywords
10-dione , Antitumor agents , Azaanthraquinones.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794167
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