Title of article
N-Alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, μ and δ opioid agonists: a μ address
Author/Authors
John R. Carson، نويسنده , , Steven J. Coats، نويسنده , , Ellen E. Codd، نويسنده , , Scott L. Dax، نويسنده , , Jung Lee، نويسنده , , Rebecca P. Martinez، نويسنده , , Linda A. McKown، نويسنده , , Lou Anne Neilson، نويسنده , , Philip M. Pitis، نويسنده , , Wu-Nan Wu، نويسنده , , Sui-Po Zhang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
2113
To page
2116
Abstract
The tertiary amide δ opioid agonist 2 is a potent antinociceptive agent. Compound 2 was metabolized in vitro and in vivo to secondary amide 3, a potent and selective μ opioid agonist. The SAR of a series of N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides was examined.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794349
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