Title of article
Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand
Author/Authors
Norikazu Nishino، نويسنده , , Daisuke Yoshikawa، نويسنده , , Louis A. Watanabe، نويسنده , , Tamaki Kato، نويسنده , , Binoy Jose، نويسنده , , Yasuhiko Komatsu، نويسنده , , Yuko Sumida، نويسنده , , Minoru Yoshida، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
2427
To page
2431
Abstract
Cyclic tetrapeptide retrohydroxamic acids were prepared as histone deacetylase (HDAC) inhibitors and evaluated the inhibitory activity and found that they have potential as anticancer drugs.
Keywords
Retrohydroxamate , inhibitor , Histone deacetylase , Cyclictetrapeptide.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794412
Link To Document