Title of article
Thiourea inhibitors of herpesviruses. Part 3: Inhibitors of varicella zoster virus
Author/Authors
Martin J. Di Grandi، نويسنده , , Kevin J. Curran، نويسنده , , Gregg Feigelson، نويسنده , , Amar Prashad، نويسنده , , Adma A. Ross، نويسنده , , Robert Visalli، نويسنده , , Jeanette Fairhurst، نويسنده , , Boris Feld، نويسنده , , Jonathan D Bloom، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
4157
To page
4160
Abstract
The preparation of α-methylbenzyl thioureas and their biological activity against varicella zoster virus is described. Several analogs demonstrated IC50s<0.1 μM and their SAR are discussed. These compounds represent a novel class of potent and selective nonnucleoside inhibitors of varicella zoster virus.
Keywords
Thiourea , inhibitors , VZV , varicella zoster virus , Novelinhibitors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794753
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