Title of article
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants
Author/Authors
Clara Cena، نويسنده , , Donatella Boschi، نويسنده , , Gian Cesare Tron، نويسنده , , Kostantin Chegaev، نويسنده , , Loretta Lazzarato، نويسنده , , Antonella Di Stilo، نويسنده , , Manuela Aragno، نويسنده , , Roberta Fruttero، نويسنده , , Alberto Gasco، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
5971
To page
5974
Abstract
A new class of NO-donor phenol derivatives is described. The products were obtained by joining appropriate phenols with either nitrooxy or 3-phenylsulfonylfuroxan-4-yloxy moieties. All the compounds proved to inhibit the ferrous salt/ascorbate induced lipidic peroxidation of membrane lipids of rat hepatocytes. They were also capable of dilating rat aorta strips precontracted with phenylephrine.
Keywords
Phenol antioxidants , nitric oxide , NO donors , NO-donorphenol antioxidants.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795106
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