• Title of article

    5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa

  • Author/Authors

    Jennifer X. Qiao، نويسنده , , Xuhong Cheng، نويسنده , , Dilip P. Modi، نويسنده , , Karen A. Rossi، نويسنده , , Joseph M. Luettgen، نويسنده , , Robert M. Knabb، نويسنده , , Prabhakar K. Jadhav، نويسنده , , Ruth R. Wexler، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    7
  • From page
    29
  • To page
    35
  • Abstract
    Syntheses and SAR studies of 5-amidinobenzo[b]thiophene analogs provided compounds with low submicromolar factor IXa activity and equal or slightly better selectivity relative to factor Xa.
  • Keywords
    Factor IXa , Anticoagulant
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795144

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=795144