Title of article
Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists
Author/Authors
Gregory H. Merriman، نويسنده , , Liang Ma، نويسنده , , Patrick Shum، نويسنده , , Daniel McGarry، نويسنده , , Frank Volz، نويسنده , , Jeffrey S. Sabol، نويسنده , , Alexandre Gross، نويسنده , , Zhicheng Zhao، نويسنده , , David Rampe، نويسنده , , Lin Wang، نويسنده , , Friederike Wirtz-Brugger، نويسنده , , Bruce A. Harris، نويسنده , , Douglas Macdonald، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
435
To page
438
Abstract
A series of 4,5-diarylimidazoline libraries were prepared using high-throughput solid-phase and microwave techniques. The compounds were evaluated as P2X7 antagonists and their SAR is described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795221
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