Title of article
A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes
Author/Authors
Sharon N. Bisaha، نويسنده , , Mary F. Malley، نويسنده , , Andrew Pudzianowski، نويسنده , , Hossain Monshizadegan، نويسنده , , Paulina Wang، نويسنده , , Cort S. Madsen، نويسنده , , Jack Z. Gougoutas، نويسنده , , Philip D. Stein، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
2749
To page
2751
Abstract
The preferred absolute configuration of two series of F1F0-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same ‘triaryl’ pharmacophore to the enzyme binding site.
Keywords
Mitochondrial ATPase , Acylguanidine , Chiral synthesis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795663
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