• Title of article

    Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat–TAR interactions: Squaryldiamide as a new potential bioisostere of unsubstituted guanidine

  • Author/Authors

    Chi-Wan Lee، نويسنده , , Hong Cao ، نويسنده , , Kozi Ichiyama، نويسنده , , Tariq M. Rana، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    4243
  • To page
    4246
  • Abstract
    By performing RNA-targeted structure–activity relationship studies, we discovered a novel peptidomimetic containing squaryldiamide as a potential bioisostere replacement for guanidine that binds transactivation responsive RNA with high affinity.
  • Keywords
    RNA–protein interactions
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795967