Title of article
Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat–TAR interactions: Squaryldiamide as a new potential bioisostere of unsubstituted guanidine
Author/Authors
Chi-Wan Lee، نويسنده , , Hong Cao ، نويسنده , , Kozi Ichiyama، نويسنده , , Tariq M. Rana، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
4243
To page
4246
Abstract
By performing RNA-targeted structure–activity relationship studies, we discovered a novel peptidomimetic containing squaryldiamide as a potential bioisostere replacement for guanidine that binds transactivation responsive RNA with high affinity.
Keywords
RNA–protein interactions
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795967
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