Title of article
Synthesis and antitubercular activity of 2-hydroxy-aminoalkyl derivatives of diaryloxy methano phenanthrenes
Author/Authors
Gautam Panda، نويسنده , , Shagufta، نويسنده , , Anil K. Srivastava، نويسنده , , Sudhir Sinha، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
5222
To page
5225
Abstract
A series of 2-hydroxy-aminoalkyl derivatives of diaryloxy methano phenanthrenes were synthesized from nucleophilic opening of oxirane with different amines. These compounds were evaluated for their antitubercular activity against Mycobacterium tuberculosis H37Rv in vitro and showed MIC in the range of 3.12–25 μg/ml.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796160
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