Title of article
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus
Author/Authors
Zhijian Lu، نويسنده , , Joann Bohn، نويسنده , , Tom Rano، نويسنده , , Carrie A. Rutkowski، نويسنده , , Amy L. Simcoe، نويسنده , , David B. Olsen، نويسنده , , William A. Schleif، نويسنده , , Anthony Carella، نويسنده , , Lori Gabryelski، نويسنده , , Lixia Jin، نويسنده , , Jiunn H. Lin، نويسنده , , Emilio Emini، نويسنده , , Kevin Chapman، نويسنده , , James R. Tata، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
5311
To page
5314
Abstract
Efforts directed to identifying potent HIV protease inhibitors (PI) have yielded a class of compounds that are not only very active against wild-type (NL4-3) HIV virus but also very potent against a panel of PI-resistant viral isolates. Chemistry and biology are described.
Keywords
HIV , protease , inhibitors
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796180
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