• Title of article

    Microbial transformation of silybin by Trichoderma koningii

  • Author/Authors

    Hyun-jung Kim، نويسنده , , Hae-Suk Park، نويسنده , , Ik-Soo Lee، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2006
  • Pages
    4
  • From page
    790
  • To page
    793
  • Abstract
    Microbial transformation of silybin A (1) and silybin B (2), the major hepatoprotective flavonolignan diastereomers from the fruits of Silybum marianum, with the culture broth of Trichoderma koningii gave two pairs of glucosylated derivatives. Their structures were identified as silybin A 3-O-β-d-glucopyranoside (3), silybin A 7-O-β-d-glucopyranoside (4), silybin B 3-O-β-d-glucopyranoside (5) and silybin B 7-O-β-d-glucopyranoside (6) by spectroscopic methods.
  • Keywords
    Silybin , microbial transformation , Trichoderma koningii , Silybin A 7-O-?-d-glucopyranoside , Silybin B 3-O-?-d-glucopyranoside , Silybin B 7-O-?-d-glucopyranoside , Silybin A 3-O-?-d-glucopyranoside
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2006
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    796461