Title of article
Asymmetric synthesis of the l-fuco-nojirimycin, a nanomolar α-l-fucosidase inhibitor
Author/Authors
Mathieu Dubernet، نويسنده , , Albert Defoin، نويسنده , , Céline Tarnus، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
1172
To page
1174
Abstract
We describe the asymmetric synthesis of the 5-amino-5-deoxy-l-fucose (l-fuco-nojirimycin) which appears as a very potent fucosidase inhibitor with a Ki value of 1 nM.
Keywords
fuco-Nojirimycin , Fucosidase inhibitors , asymmetric synthesis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796538
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