Title of article
Novel 4-N-substituted aryl pent-2-ene-1,4-dione derivatives of piperazinyloxazolidinones as antibacterials
Author/Authors
Braj Bhushan Lohray، نويسنده , , Vidya Bhushan Lohray، نويسنده , , Brijesh Kumar Srivastava، نويسنده , , Sunil Gupta، نويسنده , , Manish Solanki، نويسنده , , Purvi Pandya، نويسنده , , Prashant Kapadnis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
1557
To page
1561
Abstract
A few substituted piperazinylphenyloxazolidinone compounds 6–13 having substitution on the distant nitrogen atom of piperazine ring scaffold have been synthesized and evaluated for their antibacterial activity in Gram-positive bacteria. A few compounds showed superior in vitro antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Streptococcus pyogenes than linezolid and eperezolid.
Keywords
Piperazinylaryloxazolidinone , In vitro MIC , Linezolid , Eperezolid , Gram-positive bacteria , Antibacterials
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796619
Link To Document