Title of article
Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands
Author/Authors
Masahiko Kainuma، نويسنده , , Jun-ichi Kasuga، نويسنده , , Shinnosuke Hosoda، نويسنده , , Ken-ichi Wakabayashi، نويسنده , , Aya Tanatani، نويسنده , , Kazuo Nagasawa، نويسنده , , Hiroyuki Miyachi، نويسنده , , Makoto Makishima، نويسنده , , Yuichi Hashimoto، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
3213
To page
3218
Abstract
Novel, potent farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor α (PPARα) agonists were obtained by using a diphenylmethane skeleton as a substitute for a steroid skeleton.
Keywords
Nuclear receptor ligands , FXR , Drug design , PPAR , Diphenylmethane
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796959
Link To Document