Title of article
Two novel furan derivatives from Phellinus linteus with anti-complement activity
Author/Authors
Byung-Sun Min، نويسنده , , Bong-Sik Yun، نويسنده , , Hyeong-kyu Lee، نويسنده , , Hee-Jin Jung، نويسنده , , Hyun-Ah Jung، نويسنده , , Jae-Sue Choi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
3255
To page
3257
Abstract
Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 μM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes.
Keywords
Furan derivatives , Anti-complement activity , Phellinus linteus , structural determination
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796968
Link To Document