Title of article
Array synthesis of progesterone receptor antagonists: 3-Aryl-1,2-diazepines
Author/Authors
Robert W. Wiethe، نويسنده , , Eugene L. Stewart، نويسنده , , David H. Drewry، نويسنده , , David W. Gray، نويسنده , , Abdul Mehbob، نويسنده , , William J. Hoekstra، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
3777
To page
3779
Abstract
New non-steroidal chemotypes are required for the development of drugs targeting the steroid hormone receptors. The parallel array synthesis of 3-aryl-1,2-diazepines employing solid-supported reagents is described. The resulting compounds demonstrated high affinity binding to the progesterone receptor.
Keywords
progesterone receptor , Diazepine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797076
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