Title of article
Site-Selective DNA cleavage by a novel complex of copper-conjugate of Phen and polyamide containing N-methylimidazole rings
Author/Authors
Dan Liu، نويسنده , , Jiang Zhou، نويسنده , , Huihui Li، نويسنده , , Bo Zheng، نويسنده , , Gu Yuan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
5032
To page
5035
Abstract
A novel conjugate of 3-Clip-Phen and polyamide containing three N-methylimidazole (Im) rings was synthesized for the targeting human telomeric repeat of 5′-TTAGGG-3′, and the DNA cleaving activity and the sequence selectivity of the complex of copper-conjugate were confirmed by electrospray ionization mass spectrometry.
Keywords
ESI-mass spectrometry , Site-selective DNA cleavage , DNA cleaving activity
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797324
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