Title of article
Affinity separation of polyribonucleotide-binding human blood proteins
Author/Authors
Yuliya V. Gerasimova، نويسنده , , Irina V. Alekseyeva، نويسنده , , Tatyana G. Bogdanova، نويسنده , , Irina A. Erchenko، نويسنده , , Natalya V. Kudryashova، نويسنده , , Boris P. Chelobanov، نويسنده , , Pavel P. Laktionov، نويسنده , , Pavel V. Alekseyev، نويسنده , , Tatyana S. Godovikova، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
5526
To page
5529
Abstract
Using affinity columns with immobilized poly(A), poly(G), poly(U), poly(C), and poly(A)•poly(U) and poly(G)•poly(C) duplexes several polyribonucleotide-binding blood plasma proteins have been captured. Albumin and keratins K1 and K2e have been detected to bind polypurine tracts. The in vitro glycated albumin binds poly(A) and poly(G) more efficiently than the unmodified protein. The major polypyrimidine-binding blood plasma protein (28 kDa) can catalyze the hydrolysis of poly(U).
Keywords
Polyribonucleotide-binding proteins , Albumin , affinity chromatography , Rnase , keratins
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797420
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