Title of article
Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: Differences of bioactivity in the enantiomeric series
Author/Authors
Nolan R. Mente، نويسنده , , Andrew J. Wiemer، نويسنده , , Jeffrey D. Neighbors، نويسنده , , John A. Beutler، نويسنده , , Raymond J. Hohl، نويسنده , , David F. Wiemer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
911
To page
915
Abstract
Total synthesis of the (R,R,R)- and (S,S,S)-enantiomers of the natural product schweinfurthin F has been completed. Comparisons of spectral data and optical rotations with those reported for the natural product, as well as a variety of bioassay data, allow assignment of the natural material as the (R,R,R)-isomer.
Keywords
Schweinfurthin , Enantiomer , synthesis , activity
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797762
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