• Title of article

    3-Hydroxychromones as cyclin-dependent kinase inhibitors: Synthesis and biological evaluation

  • Author/Authors

    Jinho Lee، نويسنده , , Taesik Park، نويسنده , , ShinWu Jeong، نويسنده , , Kyoung-Hee Kim، نويسنده , , ChangYong Hong، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2007
  • Pages
    4
  • From page
    1284
  • To page
    1287
  • Abstract
    A novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiazolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDAMB468 cancer cells.
  • Keywords
    Isothiazolidine 1 , 1-dioxide , CDK2 , 3-Hydroxychromone
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2007
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    797835

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=797835