Title of article
Phosphonoxins: Rational design and discovery of a potent nucleotide anti-Giardia agent
Author/Authors
Dae-Hwan Suk، نويسنده , , Dominik Rejman، نويسنده , , Christine C. Dykstra، نويسنده , , Radek Pohl، نويسنده , , Krzysztof W. Pankiewicz، نويسنده , , Steven E. Patterson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
2811
To page
2816
Abstract
Phosphonoxins, a new class of synthetic, rationally designed anti-microbial agents, are described. From this class a sub-micromolar inhibitor of Giardia trophozoite growth has been identified.
Keywords
Giardia , Encystation , Cyst wall synthase , nucleotide
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798129
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