Title of article
Synthesis and antitumour activity of new tiazofurin analogues bearing a 2,3-anhydro functionality in the furanose ring
Author/Authors
Mirjana Popsavin، نويسنده , , Sa?a Spai?، نويسنده , , Milo? Svir?ev، نويسنده , , Vesna Koji?، نويسنده , , Gordana Bogdanovic، نويسنده , , Velimir Popsavin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
4123
To page
4127
Abstract
This paper describes a divergent de novo synthesis of 2-(2,3-anhydro-β-dribofuranosyl)thiazole-4-carboxamide (2′,3′-anhydro-tiazofurin) and the corresponding α- and β-homo-C-nucleosides, as well as evaluation of their antitumour activities in vitro.
Keywords
5-Anhydro sugars , C-Nucleosides , Antitumour agents , 2 , Homo-C-nucleosides , thiazoles , Tiazofurin analogues
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798378
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