Title of article
Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles
Author/Authors
Frederick E. Boyer، نويسنده , , J.V.N. Vara Prasad، نويسنده , , Allison L. Choy، نويسنده , , Louis Chupak، نويسنده , , Michael R. Dermyer، نويسنده , , Qizhu Ding، نويسنده , , Michael D. Huband، نويسنده , , Wenhua Jiao، نويسنده , , Takushi Kaneko، نويسنده , , Vladimir Khlebnikov، نويسنده , , Ji-Young Kim، نويسنده , , Manjinder S. Lall، نويسنده , , Samarendra N. Maiti، نويسنده , , Karina Romero، نويسنده , , Xiujuan Wu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
4694
To page
4698
Abstract
A novel series of conformationally-restricted oxazolidinones was synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituents. A number of analogs exhibited potent activity against both Gram-positive and fastidious Gram-negative organisms.
Keywords
oxazolidinones , Conformationally-restricted , Gram-positive activity , Fastidious Gram-negative activity
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798487
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