Title of article
Synthesis of novel anilinoquinolines as c-fms inhibitors
Author/Authors
Terrence L. Smalley Jr.، نويسنده , , Stanley D. Chamberlain، نويسنده , , Wendy Y. Mills، نويسنده , , David L. Musso، نويسنده , , Sab A. Randhawa، نويسنده , , John A. Ray، نويسنده , , Vicente Samano، نويسنده , , Lloyd Frick، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
6257
To page
6260
Abstract
A novel series of potent substituted anilinoquinolines were discovered as c-fms inhibitors. The potency could be manipulated upon modification of the C4 aniline and C7 aryl functionality. Pharmacokinetic analysis identified a metabolically stable analog suitable for further investigative work.
Keywords
kinase , inhibitors , inflammation
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798786
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