• Title of article

    5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  • Author/Authors

    Kazutoshi Watanabe، نويسنده , , Yasuhiro Morinaka، نويسنده , , Yoshio Hayashi، نويسنده , , Masaki Shinoda، نويسنده , , Hiroyoshi Nishi، نويسنده , , Nobuko Fukushima، نويسنده , , Toshiaki Watanabe، نويسنده , , Akira Ishibashi، نويسنده , , Satoshi Yuki، نويسنده , , Masahiko Tanaka، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    6
  • From page
    1478
  • To page
    1483
  • Abstract
    A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation.
  • Keywords
    antioxidant , Imidazolin-2-one , radical scavenger
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2008
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    799190