Title of article
Chrobisiamone A, a new bischromone from Cassia siamea and a biomimetic transformation of 5-acetonyl-7-hydroxy-2-methylchromone into cassiarin A
Author/Authors
Shiori Oshimi، نويسنده , , Yuichiro Tomizawa، نويسنده , , Yusuke Hirasawa، نويسنده , , Toshio Honda، نويسنده , , Wiwied Ekasari، نويسنده , , Aty Widyawaruyanti، نويسنده , , Marcellino Rudyanto، نويسنده , , Gunawan Indrayanto، نويسنده , , Noor Cholies Zaini، نويسنده , , Hiroshi Morita، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
3761
To page
3763
Abstract
A new bischromone, chrobisiamone A (1) with an antiplasmodial activity has been isolated from the leaves of Cassia siamea and the structure was elucidated by 2D NMR analysis. Cyclization of 5-acetonyl-7-hydroxy-2-methylchromone (2) in the presence of ammonium acetate resulted in generation of cassiarin A (3) with an unprecedented tricyclic skeleton, supporting a biogenetic pathway proposed for 3.
Keywords
Chrobisiamone A , Bischromone , Antiplasmodial activity , Biomimetic transformation , Cassia siamea
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799651
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