Title of article
Improvement of the transactivation activity of phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists: Effect of introduction of fluorine at the linker part
Author/Authors
Jun-ichi Kasuga، نويسنده , , Takuji Oyama، نويسنده , , Yuko Hirakawa، نويسنده , , Makoto Makishima، نويسنده , , Kosuke Morikawa، نويسنده , , Yuichi Hashimoto، نويسنده , , Hiroyuki Miyachi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
4525
To page
4528
Abstract
We developed a potent peroxisome proliferator-activated receptor pan agonist (a candidate drug for treatment of altered metabolic homeostasis) by introducing fluorine atoms at appropriate position(s) of the known phenylpropionic acid-type pan agonist TIPP-703.
Keywords
Fluorine , PPAR pan agonist , PPAR
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799820
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