• Title of article

    Selective inhibitory effects of hybrid liposomes on the growth of HIV type 1-infected cells in vitro

  • Author/Authors

    Ryuichi Ueoka، نويسنده , , Yuji Komizu، نويسنده , , Yoko Matsumoto، نويسنده , , Yu Zhong، نويسنده , , Ritsuko Tanaka، نويسنده , , Naoki Yamamoto، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    3
  • From page
    4578
  • To page
    4580
  • Abstract
    A good correlation between fifty-percent inhibitory concentration (IC50) of hybrid liposomes (HL) composed of dimyristoylphosphatidylcholine and polyoxyethylene(n) dodecyl ether on the growth of MOLT-4/IIIB cells (MOLT-4 cells chronically infected with human immunodeficiency virus (HIV)) and the membrane fluidity of HL was obtained. Furthermore, the huge enhancement of virus production was observed in the latently HIV-infected (J22-HL-60) cells after the treatment with HL.
  • Keywords
    Liposome , HIV-1 , Membrane fluidity , latency , growth inhibition , Virus production
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2008
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    799833