Title of article
PNA/DNA interstrand cross-links from a modified PNA base upon photolysis or oxidative conditions
Author/Authors
Yongtae Kim، نويسنده , , In Seok Hong، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
5054
To page
5057
Abstract
PNA/DNA interstrand cross-links (ICLs) were observed when peptide nucleic acids (PNAs) containing modified thymine derivatives were hybridized with the complementary or one-base mismatched DNA upon photolysis or treatments of oxidative agent. PNA/DNA ICL formation provides a useful method for biological applications such as antisense technologies or PNA chips.
Keywords
Oxidative condition , peptide nucleic acid , Interstrand cross-links , photolysis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799947
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