Title of article
Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp.
Author/Authors
Dongha Lee، نويسنده , , Jongheon Shin، نويسنده , , Kyung-Mi Yoon، نويسنده , , Tae-Im Kim، نويسنده , , Woo Hyoung Lee ، نويسنده , , Hyi-Seung Lee، نويسنده , , Ki-Bong Oh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
5377
To page
5380
Abstract
Seven sesterterpene sulfates (1–7) were isolated from the tropical sponge Dysidea sp. and their inhibitory activities against isocitrate lyase (ICL) from Candida albicans were evaluated. Among the isolated natural products compound 6 and 7 were found to be strong ICL inhibitors. The isolated compounds (1–7) also showed potent antibacterial effect against Bacillus subtilis and Proteus vulgaris, but did not display antifungal activity.
Keywords
Sponge , Dysidea sp. , Antibacterial activity , Isocitrate lyase inhibition , Sesterterpene sulfates
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800016
Link To Document