Title of article
Synthesis and P2Y receptor activity of a series of uridine dinucleoside 5′-polyphosphates
Author/Authors
William Pendergast، نويسنده , , Benjamin R. Yerxa، نويسنده , , James G. Douglass III، نويسنده , , Sammy R. Shaver، نويسنده , , Robert W. Dougherty، نويسنده , , Catherine C. Redick، نويسنده , , Ingrid F. Sims، نويسنده , , Janet L. Rideout، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
157
To page
160
Abstract
A series of dinucleoside 5-polyphosphates UpnU (n=2–7) was synthesized. Their relative potencies as agonists at the G-protein-coupled receptors P2Y1, P2Y2, P2Y4, and P2Y6 were determined by intracellular calcium measurements using fluorescent imaging techniques. The correlation of phosphate chain length to activities at these receptors is discussed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800298
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