• Title of article

    Securiosides A and B, novel acylated triterpene bisdesmosides with selective cytotoxic activity against M-CSF-stimulated macrophages

  • Author/Authors

    Minpei Kuroda، نويسنده , , Yoshihiro Mimaki، نويسنده , , Yutaka Sashida، نويسنده , , Mikio Kitahara، نويسنده , , Masatoshi Yamazaki*، نويسنده , , Satoru Yui، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    371
  • To page
    374
  • Abstract
    We report the discovery of securiosides A (1) and B (2), novel acylated triterpene bisdesmosides, isolated from the roots of Securidaca inappendiculata. Securiosides A and B showed potent selective cytotoxic activity against M-CSF-stimulated macrophages and were suggested to have potential as new agents for the treatment of inflammatory diseases such as RA and atherosclerosis.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    800349

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=800349