Title of article
Synthesis and biological evaluation of DNA targeting flexible side-chain substituted β-carboline derivatives
Author/Authors
Sulong Xiao، نويسنده , , Wei Lin، نويسنده , , Chao Wang، نويسنده , , Ming Yang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
5
From page
437
To page
441
Abstract
A series of 3-substituted-β-carboline derivatives was synthesized from -tryptophan. The intercalating binding mode of these compounds with DNA, the effects of the flexible alkylamine side chain on the intercalating ability and their antitumor activity were studied, which agreed well with the molecular modeling results.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800366
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