• Title of article

    Synthesis and structure–activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells

  • Author/Authors

    Haruhisa Ogita، نويسنده , , Yoshiaki Isobe، نويسنده , , Haruo Takaku، نويسنده , , Rena Sekine، نويسنده , , Yuso Goto، نويسنده , , Satoru Misawa، نويسنده , , Hideya Hayashi، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    549
  • To page
    551
  • Abstract
    A series of diarylamide derivatives were synthesized and evaluated for their inhibitory activities against human coronary artery smooth muscle cells (SMCs) and human coronary artery endothelial cells (ECs). Compound 2w was superior to the lead compound, Tranilast, in terms of the potency of the activity and cell selectivity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    800392