Apical hypertrophic cardiomyopathy with midventricular obstruction and apical aneurysm

We present the case of a 69-year-old female with a long history of apical hypertrophic cardiomyopathy progressing to midcavitary obstruction and apical aneurysm development. A coronary angiogram showed no stenotic lesions in the epicardial coronary arteries and myocardial perfusion imaging showed no perfusion defects in the left ventricular apex, with the latter being an extremely uncommon finding. This case suggests that apical aneurysm may not be exclusively caused by ischemia and eventually different or coexisting factors are probably involved.