Title of article
How should the efficacy of novel treatments be assessed in survival trials?
Author/Authors
A. Owen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
297
To page
300
Abstract
Survival trials tend to have the results presented in relative terms, usually using the hazard ratio. When absolute treatment effects are presented this is often done in terms of the Number Needed to Treat concept. For many medical treatments this approach is biologically implausible and can be misleading. The mean survival time approach leading to the absolute treatment effect in terms of extra life years is rarely used. It is suggested that this approach has many advantages over the Number Needed to Treat approach and should be used to present the absolute treatment effect in survival trials.
Keywords
Survival , Mean survival time , Life expectancy , number needed to treat
Journal title
International Journal of Cardiology
Serial Year
2007
Journal title
International Journal of Cardiology
Record number
815363
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