• Title of article

    How should the efficacy of novel treatments be assessed in survival trials?

  • Author/Authors

    A. Owen، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2007
  • Pages
    4
  • From page
    297
  • To page
    300
  • Abstract
    Survival trials tend to have the results presented in relative terms, usually using the hazard ratio. When absolute treatment effects are presented this is often done in terms of the Number Needed to Treat concept. For many medical treatments this approach is biologically implausible and can be misleading. The mean survival time approach leading to the absolute treatment effect in terms of extra life years is rarely used. It is suggested that this approach has many advantages over the Number Needed to Treat approach and should be used to present the absolute treatment effect in survival trials.
  • Keywords
    Survival , Mean survival time , Life expectancy , number needed to treat
  • Journal title
    International Journal of Cardiology
  • Serial Year
    2007
  • Journal title
    International Journal of Cardiology
  • Record number

    815363