Is the use of ABPM justified in patients on 1 or 2 antihypertensive medications?

We studied the utility of ABPM in patients with elevated clinic BP on 1–2 antihypertensive medications (group B, N = 117), compared with those on no medications (group A, N = 76) and on ≥ 3 medications (group C, N = 110). 35% of patients in group B had adequately controlled 24-h BP based on ABPM, compared with 22.4% in group A (P = 0.06) and 19.1% in group C (P = 0.007). Antihypertensive treatment was not escalated in patients with adequately controlled BP. This suggests that ABPM has an important role in therapeutic decision-making for patients on 1–2 antihypertensive medications.