Title of article
Manipulation with heterogeneity within a species population formulated as an inverse problem
Author/Authors
D. Horv?th، نويسنده , , B. Brutovsky، نويسنده , , J. Ko?i?ov?، نويسنده , , S. ?princ، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
9
From page
5028
To page
5036
Abstract
Dependence of the evolutionary dynamics on the population’s heterogeneity has been reliably recognized and studied within the frame of evolutionary optimization theory. As the causal relation between the heterogeneity and dynamics of environment has been revealed, the possibility to influence convergence rate of evolutionary processes by purposeful manipulation with environment emerges.
For the above purposes we formulate the task as the inverse problem meaning that desired population heterogeneity, quantified by Tsallis information entropy, represents the model’s input and dynamics of environment leading to desired population heterogeneity is looked for. Here the presented abstract model of evolutionary motion within the inverse model of replicating species is case-independent and it is relevant for the broad range of phenomena observed at cellular, ecological, economic and social scales. We envision relevance of the model for anticancer therapy, in which the effort is to circumvent heterogeneity as it typically correlates with the therapy efficiency.
Journal title
Physica A Statistical Mechanics and its Applications
Serial Year
2010
Journal title
Physica A Statistical Mechanics and its Applications
Record number
873941
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