Two-parameters Hopf bifurcation in the Hodgkin–Huxley model

In this paper, the Hodgkin–Huxley model is studied with the leakage conductance and the sodium reversal potential selected as parameters for a two-parameter Hopf-bifurcation analysis. The influence of bifurcation on the HH model was also discussed and algebra criterion in high dimension equations was used to identify Hopf bifurcation. In addition, this paper also discuses the bifurcation approach to inherited disorders of ion channels in skeletal muscle excitable membranes.