Title of article
Addressing cell-sourcing limitations with gene therapy
Author/Authors
A.J.، Garcia, نويسنده , , R.E.، Guldberg, نويسنده , , B.A.، Byers, نويسنده , , C.A.، Gersbach, نويسنده , , J.E.، Phillips, نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
-64
From page
65
To page
0
Abstract
Genetic engineering with Run*2/Cbfa 1 for an alternative to biological grafts. Forced Runx2 expression via retroviral gene delivery promotes osteoblastic differentiation and mineralization in bone marrow stromal cells and stimulates conversion of myoblasts and dermal fibroblasts into a mineralizing osteoblastic phenotype. This genetic engineering strategy provides a promising approach to overcome cell-sourcing limitations in bone tissue engineering.
Keywords
Quantum dots , Fluorescence resonance energy transfer , immunoglobulin G
Journal title
IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE
Serial Year
2003
Journal title
IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE
Record number
92078
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